St. Louis Children's Hospital
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Principal Investigators
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Institution
Founded in 1879, St. Louis Children’s Hospital (SLCH) is at the forefront of pediatric medicine, providing care for children around the world. As the pediatric teaching hospital for Washington University School of Medicine (WUSM), SLCH offers nationally recognized programs for training and research. Nationally recognized as a Best Children’s Hospital by U.S. News & World Report, the 258-bed hospital includes a 36-bed pediatric intensive care unit (including a 12-bed cardiac intensive care unit), a 70-bed Level IV newborn intensive care unit and a 6-bed pediatric bone marrow transplant unit. St. Louis Children’s Hospital is a Magnet® designated hospital.
The Pediatric Neuro-Oncology Center at SLCH/WUSM offers a comprehensive, compassionate, diagnosis and treatment of pediatric tumors in the brain and spinal cord. Members of the multi-disciplinary team include pediatric neuro-oncologists, neurosurgeons, radiation oncologists, radiologists, pathologists, endocrinologists, psychologists, and other specialty staff. SLCH has access to the latest therapeutic options for children with brain tumors, including intra-operative MRI, advanced imaging modalities, and proton beam radiation therapy.
Affiliated with WUSM, the Siteman Cancer Center has an international reputation for patient care and education, as well as cancer research. The Pediatric Neuro-Oncology Program at WUSM has active basic, translational and clinical science research programs. The research programs at SLCH and WUSM benefit from a primary brain tumor-banking program that includes extensive clinical annotation of viable as well as fixed and frozen archived specimens, a high-throughput screening core for preclinical compound library screens, a genomic engineering core, cutting edge small-animal imaging facilities and a world renown genomic sciences center. Collaborative lab-based and clinical research efforts are coordinated through several monthly group meetings focused on the genomics and epigenomics, stem cell biology, experimental imaging and mechanisms of therapeutic response and resistance in pediatric brain tumors.