Investigating biomarker for treatment respondors and non-respondors in PDX model experiment.

Ongoing
Data
HGG
DIPG
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CBTN Data Used

About this

Project

Children with high-grade glioma, diffuse intrinsic pontine glioma, rhabdoid brain tumors, and certain other types of brain tumors experience a low likelihood of survival even with maximal therapy, including surgery, intensive chemotherapy, and radiation therapy.

Ask The

Scientists

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What are the goals of this project?

The goal of this project is to find alternative to the often toxic standard therapies for the pediatric patient mentioned by searching for particular class of combination of drugs. One of outcome of this research is also finding biomarkers that are correlated with responders and non-responders with combination therapy we are trying in PDX animal models.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.

Explore the data in these informatics portals

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