About this

Project

For this project, tumors of the specific diagnoses of neurocytoma were identified for whole-genome and RNA sequencing. Whole genome sequencing involves identifying all of the base chemicals that make up the DNA in a genome. RNA sequencing involves analyzing for the presence and quantity of RNA. Both of these analyses are integral in the field of cancer biology and cancer treatment because they help researchers better understand how a tumor forms, grows, and persists. The goal of this project is to perform whole genome and RNA sequencing on neurocytomas. The Children's Brain Tumor Network contributed to the project by providing germline and tumor DNA and tumor RNA for use by investigators. The information gained from this work could lead to advances in treatment for patients with neurocytoma.

Ask The

Scientists

Ask the scientists

What are the goals of this project?

Researchers will conduct RNA and whole genome sequencing on neurocytoma samples in an effort to better understand their formation and persistence.

What is the impact of this project?

This project will fill a knowledge gap about neurocytoma and could lead to advancements in treatment for this disease. The data generated will be shared will all researchers.

Why is the CBTN request important to this project?

Quality specimens are hard to come by in the field of pediatric brain cancers, but the Children’s Brain Tumor Network provides researchers with quality neurocytoma specimens with which they can complete this work.

Specimen Data

The Children's Brain Tumor Network contributed to the project by providing germline and tumor DNA and tumor RNA.