Understanding the genetic makeup of tumors is crucial in the pursuit of diagnostics and therapies. Sequencing a tumor sample’s DNA, or identifying all of the genes present in the tumor, is important for better understanding cancers and creating treatments. However, genomic data is not the only clinically relevant information for diagnosing cancer. Researchers on this project seek to combine genomic data with tumor imagery and text-based data gathered directly from patients and medical professionals. Comparing this data could reveal connections and patterns relevant to more accurate diagnoses,effective treatments and better understand different tumor types. Using machine learning-based algorithms, or instructions for a computer that adapt themselves to new information, researchers will compare text-based clinical data provided by CBTN to genomic data made available through the Pediatric Brain Tumor Atlas. With access to such a broad dataset on pediatric brain cancers, researchers aim to improve the accuracy of diagnostic tests for pediatric patients.
What are the goals of this project?
Researchers are looking for correlations between genomic data, text-based data, and tumor imagery of pediatric brain cancers.
What is the impact of this project?
By combining analysis of these data types, researchers hope to improve the diagnostic accuracy of current.
Why is the CBTN request important to this project?
The Pediatric Brain Tumor Atlas provides researchers with the genomic data necessary for this project. This data will be supplemented with clinical data from CBTN, allowing for the comparative analysis key to this project.
The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas and clinical data.
Birra Taha, MD
Jeffrey Greenfield, MD, PhD
Dr. Greenfield’s directs multiple research projects pertaining to pediatric brain tumors, in particular, basic research examining the brain tumor microenvironment, tumor immunology, and precision medicine. This research has been externally funded and widely published and he has received national awa
Weill Cornell Medicine
Benjamin Hartley, MD
Benjamin Rush Hartley received his medical degree in 2015 from the State University of New York Downstate College of Medicine, where he was inducted into the Gold Foundation Humanism Honor Society and was awarded the Downstate Alumni Association Research Fellowship, multiple American Anatomy Associa
Weill Cornell Medicine
Weill Cornell MedicineJoined on
The Weill Cornell Medicine Pediatric Brain and Spine Center, located on the Upper East Side campus of New York-Presbyterian/Weill Cornell Medical Center, is nationally recognized for its leadership in the treatment of disorders of the central nervous system in children, particularly brain and spinal