Annie Huang
About
Principal Investigator and Associate Chair of Research, Department of Paediatrics, SickKids
She started the RBTC to pursue her long-standing research and clinical interest in rare infant brain tumours due to the distinct clinical challenges of these patient population. In her laboratory she combines genomics, functional epigenomics and genome-wide screening tools to understand the pathogenesis of rare CNS embryonal tumours, including ATRTs (Atypical Teratoid Rhabdoid tumours), and ETMRs (Embryonal Tumour with Multi-layered Rosettes) with the goal to improve treatment and patient survival.
Expertise
Neuro-oncology
Sick Kids
research
Interests
Atypical Teratoid/Rhabdoid Tumor
Central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT) is a very rare, fast-growing tumor of the brain and spinal cord. It usually occurs in children aged three years and younger, although it can occur in older children and adults. About half of these tumors form in the cerebellum or
Embryonal Tumor with Multilayered Rosettes
Nonmedulloblastoma embryonal tumors are fast-growing tumors that usually form in brain cells in the cerebrum, and most commonly occur in young children. The cerebrum is at the top of the head and is the largest part of the brain. The cerebrum controls thinking, learning, problem-solving, emotions, s