Director, Neuropathology and Ophthalmic Pathology
Johns Hopkins Medicine
Dr. Charles Eberhart is a professor of pathology, oncology, and ophthalmology, at the Johns Hopkins University School of Medicine. His research primarily focuses on molecular genetics and treatment of medulloblastoma, glioblastoma, uveal melanoma and other tumors of the brain and eye. Dr. Eberhart serves as the director of the Divisions of Neuropathology and Ophthalmic Pathology.
Major research areas in his laboratory include targeting Notch and other developmentally important signaling pathways in tumors, identifying the genetic drivers of rare neoplasms in the brain and eye, and building new models of tumors using neural stem cells.
Medulloblastomas comprise the vast majority of pediatric embryonal tumors and by definition arise in the posterior fossa, where they constitute approximately 40% of all posterior fossa tumors. Other forms of embryonal tumors each make up 2% or less of all childhood brain tumors.The clinica