Medical Director of Hematology-Oncology at Connecticut Children’s; Professor at The Jackson Laboratory
The Jackson Laboratory
Ching Lau serves as the Medical Director of Hematology-Oncology at Connecticut Children’s, as Professor at JAX where he specializes in pediatric brain and bone tumor research, and as Head of the Division of Pediatric Hematology-Oncology in the Department of Pediatrics at the UConn School of Medicine. His clinical interests include neuro-oncology, solid tumors, and osteosarcoma.
Development of Preclinical Models of Pediatric Ependymoma
Development of targeted therapy against ependymomas has been hampered by the lack of robust preclinical models. In addition, earlier genomic profiling of ependymomas failed to identify recurrent mutations in these tumors. With the discovery of the recurrent C11orf95/RELA translocation in supraten
Ching Ching Lau
Ependymomas arise from ependymal cells that line the ventricles and passageways in the brain and the center of the spinal cord. Ependymal cells produce cerebrospinal fluid (CSF). These tumors are classified as supratentorial or infratentorial. In children, most ependymomas are infratentorial tumo