Pediatric Hematology & Oncology Specialist
Hackensack University Medical Center
Dr. Derek Hanson is the Section Chief of Pediatric Neuro-oncology at the Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center. He received his medical degree from Rutgers New Jersey Medical School. Following graduation he completed his pediatric residency at the Alfred I. duPont Hospital for Children and his pediatric hematology/oncology fellowship at Cohen Children’s Medical Center of New York. He then completed a pediatric neuro-oncology fellowship at the Dana-Farber Cancer Institute.
Dr. Hanson’s clinical research is focused on early phase trials for children with brain tumors. He has developed a number of phase I trials investigating new treatments for pediatric gliomas and ependymomas. His lab at Hackensack Meridian Health’s Center for Discovery and Innovation focuses on translational research to bring new brain tumor therapies from the bench to the bedside.
Dr. Hanson has a special interest in ETMR and has made it his goal to find better cures for children with this tumor. He has worked with physicians from across the globe to develop a specialized treatment protocol for children with ETMR, which is now available through the ETMR One Registry. In addition to caring for his own patients, he has worked with families of ETMR patients around the world to provide consultation and help parents find the best treatment for their children.
Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center
Elucidating the ETMR Microenvironment using Next Generation Imaging and Multi-omics Technologies
The tumor microenvironment, the cells and molecules surrounding a tumor, can provide great insight into possible therapies. Using data and samples from CBTN, researchers will assess the tumor microenvironment of embryonal tumors with multilayered rosettes. (ETMR)
Characterizing the Prevalence of ETMR by Molecular Signature
Embryonal tumors with multilayer rosettes (ETMR) have recently been reclassified and clinical investigations are needed to understand their occurrence and prevalence. ETMR specimens from the Pediatric Brain Tumor Atlas will be used by researchers to begin building a robust understanding and characterization of the tumor.
Ependymomas arise from ependymal cells that line the ventricles and passageways in the brain and the center of the spinal cord. Ependymal cells produce cerebrospinal fluid (CSF). These tumors are classified as supratentorial or infratentorial. In children, most ependymomas are infratentorial tumors
Children's Brain Tumor Network - Accelerating Research Through Collaboration and Open Science
This presentation highlights the impact and importance of the collaborative and open source nature of CBTN databases and samples.
Jena Lilly, Jennifer Mason, Elizabeth Appert, Allison Heath, Yuankun Zhu, Bo Zhang, Mateusz Koptyra, Mariarita Santi, Ian Pollack, Stewart Goldman, Sarah Leary, Anna Buccoliero, Mirko Scagnet, David Haussler, Derek Hanson, Jiangguo Zhang, Weiqing Wan, Chunde Li, Ron Firestein, Jason Cain, Joanna Phillips, Nalin Gupta, Sabine Mueller, Gerald Grant, Michelle Monje-Deisseroth, Sonia Partap, Jeffrey Greenfield, Brian Rood, Javad Nazarian, Eric Raabe, Eric Jackson, Stacie Stapleton, Robert Lober, David Kram, Phillip Storm, Rishi Lulla, Michael Prados, Adam Resnick, and Angela Waanders