Embryonal tumors with multilayer rosettes (ETMR) are a rare and highly-aggressive tumor occurring in children. Historically, the tumor that is now defined as ETMR was considered to belong to a group of tumors known as CNS-PNET. As a group, CNS-PNETs were believed to represent approximately 3-7% of all pediatric brain tumor cases, however ETMR is extremely rare with less than 300 cases reported in medical literature. Due to its rarity and recent reclassification, clinical investigations of this tumor are still evolving and the incidence and prevalence of ETMR is unknown. Using specimen data from the Pediatric Brain Tumor Atlas, researchers aim to understand the prevalence of ETMR, informing future studies into the tumor.
What are the goals of this project?
Researchers will do comprehensive analysis of ETMR specimens in an effort to better understand this rare tumor type.
What is the impact of this project?
Due to their rarity and recent reclassification, comprehensive studies into ETMR such as this one are necessary to pave the way for new diagnostics and therapies.
Why is the CBTN request important to this project?
The Pediatric Brain Tumor Atlas enables researchers to complete this work with access to rare specimens of ETMR.
The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.
Derek Hanson, MD
Dr. Derek Hanson is the Section Chief of Pediatric Neuro-oncology at the Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center. He received his medical degree from Rutgers New Jersey Medical School. Following graduation he completed his pediatric residency at the Alfred I. du
Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center
Angela Waanders, MD, MPH
Specialties:Hematology, Oncology, Neuro-Oncology & Stem Cell TransplantationEducation: Tulane University School of Medicine, 2003Postgraduate Training: Fellowship in pediatric hematology/oncology, Children's Hospital of Philadelphia, 2006-2009; Residency is pediatrics, Children's Hospital of Philade
Ann & Robert H. Lurie Children’s Hospital of Chicago
Joseph M. Sanzari Children’s Hospital at Hackensack University Medical CenterJoined on
Hackensack Meridian Children’s Health has repeatedly ranked as a top provider of pediatric health care in the United States. Ranked by U.S. News & World Report, the combined pediatric cancer care program at Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center and K. Hovnani
Ann & Robert H. Lurie Children’s Hospital of ChicagoJoined on
Ann & Robert H. Lurie Children’s Hospital of Chicago treats 220 new patients each year with pediatric cancers. The hospital is ranked 17th in the nation for their pediatric oncology program and 11th for their neurology and neurosurgery program by U.S. News & World Report.Established in 1986, the Lur