Instructor in Pediatrics
Memorial Sloan Kettering Cancer Center-Weill Cornell Medical College
Investigating the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells.
Microglial Mosaicism in BRAFV600E Glioma Development
Pediatric low grade gliomas require further research to better understand differences in tumor aggressiveness. Using tissue and blood cell samples provided by the Children’s Brain Tumor Network, researchers will explore those differences in the pursuit of therapeutic vulnerabilities.
HGG, LGG, Ganglioglioma
High-grade Gliomas (HGG) or astrocytomas in children nearly always result in a dismal prognosis. Although novel therapeutic approaches are currently in development, preclinical testing has been limited, due to a lack of pediatric-specific HGG preclinical models. These models are needed to help test
Low-Grade Gliomas also called astrocytomas are the most common cancer of the central nervous system in children. They represent a heterogeneous group of tumors that can be discovered anywhere within the brain or spinal cord. Although surgical resection may be curative, up to 20% of children still su