Clinical Research Assistant
ICON Government and Public Health Solutions
Madhuri Kambhampati is an expert in IRB and IACUC protocol management. She has over 10 years of experience in managing pediatric brain tumor biobank, skilled in coordination of pediatric post mortem tissue donation.
Scientific Reports - Nature
Harmonization of Postmortem Donations for Pediatric Brain Tumors and Molecular Characterization of Diffuse Midline Gliomas
Children diagnosed with brain tumors have the lowest overall survival of all pediatric cancers. Recent molecular studies have resulted in the discovery of recurrent driver mutations in many pediatric brain tumors. However, despite these molecular advances, the clinical outcomes of high grade tumors,
Kambhampati M, Panditharatna E, Yadavilli S, Saoud K, Lee S, Eze A, Almira-Suarez MI, Hancock L, Bonner ER, Gittens J, Stampar M, Gaonkar K, Resnick AC, Kline C, Ho C-Y, Waanders AJ, Georgescu M-M, Rance NE, Kim Y, Johnson C, Rood BR, Kilburn LB, Hwang EI, Mueller S, Packer RJ, Bornhorst M, Nazarian J.
Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
Developing targeted therapies for diffuse intrinsic pontine gliomas requires molecular understanding of the disease. Utilizing data provided by CBTN researchers work to deepen such understanding as it relates to histone mutation H3K27M.
Surya Nagaraja, Michael A. Quezada, Shawn M. Gillespie, Marlene Arzt, James J. Lennon, Pamelyn J. Woo, Volker Hovestadt, Madhuri Kambhampati, Mariella G. Filbin, Mario L. Suva, Javad Nazarian, Michelle Monje