Professor of Pediatrics at the Children's Hospital of Philadelphia
Children's Hospital of Philadelphia
Michael J. Fisher, MD, is Chief of the Section of Neuro-Oncology, Director of the Neuro-Oncology Fellowship Program and Director of the Neurofibromatosis Program at Children's Hospital of Philadelphia. He has a special interest in brain tumors and neurofibromatosis.
Areas of Expertise: Neurofibromatosis (NF) and NF-related tumors, Optic pathway gliomas, Low-grade gliomas, Plexiform neurofibromas, Pediatric brain tumors, Atypical teratoid rhabdoid tumor, Medulloblastoma
Target Identification and modeling of NF1-associated low-grade glioma
Low grade gliomas (LGG) develop in ~20% of children with NF1, occurring most commonly within the optic pathway (optic pathway glioma; OPG). While the majority of these tumors are indolent pilocytic astrocytomas (Pas) which do no necessitate medical intervention, 30-50% of the NF1-OPGs cause visua
Michael J. Fisher
Low-Grade astrocytomas are the most common cancer of the central nervous system in children. They represent a heterogeneous group of tumors that can be discovered anywhere within the brain or spinal cord. Although surgical resection may be curative, up to 20% of children still suffer from the eff