Paul Northcott

PhD

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Memphis, TN USA

St. Jude Children's Research Hospital

About

Associate Member

St. Jude Children's Research Hospital

Integrative genomics to discover genes and pathways driving pediatric brain tumorigenesis
Developmental biology of pediatric brain tumors including their cellular origins
Generation of preclinical models recapitulating the molecular features of pediatric brain tumors

St. Jude Children's Research Hospital

262 Danny Thomas Place, Memphis, TN 38105

scientific

Projects

Specimen

Data

Ongoing

Integrative Functional Genomics of Recurrent Childhood Medulloblastoma…

Medulloblastoma relapse is unfortunately common and leaves patients with a poor prognosis. Researchers will use tumor samples and data provided by the Children’s Brain Tumor Network to better understand medulloblastoma relapse, how tumors evolve, and the mechanisms of metastasis in an effort to design effective therapeutic strategies.

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Medulloblastoma

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Javad Nazarian

Children’s National Hospital

Washington, DC, USA

research

Interests

Medulloblastoma…

Medulloblastomas comprises the vast majority of pediatric embryonal tumors and by definition arise in the posterior fossa, where they constitute approximately 40% of all posterior fossa tumors. Other forms of embryonal tumors each make up 2% or less of all childhood brain tumors.The clinical feature