Aflac Cancer and Blood Disorders Center Children's Healthcare of Atlanta Emory University School of Medicine
Targeting Medulloblastoma by Regulating RNA Binding Proteins
RNA-binding proteins (RBP) may play critical roles in medulloblastoma development studying their roles will provide additional direct and indirect targets for the treatment of these tumors and beyond. Researchers will utilize cell lines provided by the Children’s Brain Tumor Network in an effort to identify new targets in the pediatric forms of these tumors.
Medulloblastomas comprises the vast majority of pediatric embryonal tumors and by definition arise in the posterior fossa, where they constitute approximately 40% of all posterior fossa tumors. Other forms of embryonal tumors each make up 2% or less of all childhood brain tumors.The clinical feature
Atypical Teratoid/Rhabdoid Tumor
Central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT) is a very rare, fast-growing tumor of the brain and spinal cord. It usually occurs in children aged three years and younger, although it can occur in older children and adults. About half of these tumors form in the cerebellum or