Trevor Pugh

Low grade gliomas are the most prevalent brain cancer among children and deeper study is needed to steer treatment protocol for patients that experience recurrence. Using samples provided by the Children’s Brain Tumor Network, researchers hope to better understand this disease and to identify new therapies.

The study of a tumor’s immune repertoire includes an analysis of T cell receptors and B cell receptors that allow an immune system to adapt to changes and launch an immune system response. Using the Pediatric Brain Tumor Atlas, researchers will study the immune repertoire across tumor types which could lead to new immunotherapies.