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CBTN

What is the CBTN

Member Institutions

Research Collaborators

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Scientific Projects

Brain Tumor Types

Publications

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Informatics Portals

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Pediatric Brain Tumor Atlas

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Research Collaborators

Zhiguo Zhang

PhD
Send EmailVisit Website

New York, NY 10032, USA

Columbia University

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About

Professor of Epigenomics and Molecular Biology

Columbia University

Epigenetic inheritance and cancer epigenetics

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Columbia University

New York, NY, USA

scientific

Projects

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Specimen

Ongoing

Elucidate Potential Therapeutic Targets in H3.3G34 Mutant pHGG cells…

Histone mutations have been identified as drivers of some pediatric brain cancers. Researchers seek to understand the role of such mutations in the development of pediatric high grade gliomas through analysis of rare specimens provided by the Children’s Brain Tumor Network.

…

HGG

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Zhiguo Zhang

Columbia University
New York, NY, USA

research

Interests

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High-Grade Glioma…

High-grade Gliomas (HGG) or astrocytomas in children nearly always result in a dismal prognosis. Although novel therapeutic approaches are currently in development, preclinical testing has been limited, due to a lack of pediatric-specific HGG preclinical models. These models are needed to help test

…
348
Participants
63
Projects Supported
Brainstem Glioma.png

Diffuse Intrinsic Pontine Glioma…

A presumptive diagnosis of DIPG based on classic imaging features, in the absence of a histologic diagnosis, has been routinely employed. Increasingly however, histologic confirmation is obtained for both entry into research studies and molecular characterization of the tumor.[5] New approaches with

…
136
Participants
31
Projects Supported

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