Integrative Analysis of Childhood Cancers
Email Principal Investigator
About this
Project
Treating pediatric cancers requires a robust understanding of the mechanisms of tumor growth and progression, as well as an understanding of the differences between tumor types. This project seeks to generate mutational, transcriptional, and integrative profiles of individual tumors. Researchers will compare samples to each other to find sub-groupings of samples, and determine which features define those groupings. Understanding these groupings could lead to the identification of targets for therapeutics. The purpose of these comparisons will be to further refine the set of potential gene and pathway targets for the treatment of pediatric brain cancers. Researchers will apply integrative analysis of data types to find potential novel drug targets and matching of therapeutics. The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.
Ask The
Scientists
What are the goals of this project?
Researchers will analyze pediatric cancer data to characterize key elements of the tumors.
What is the impact of this project?
Understanding the key characteristics for tumor types will provide improvement to identify potential new diagnostic indicators and therapeutic targets.
Why is the CBTN request important to this project?
Work like this project requires comprehensive, high quality data across cancer types, making access to the Pediatric Brain Tumor Atlas integral.
Specimen Data
The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.
Explore the data in these informatics portals
Meet The
Team
Collaborators:
- Zack Sanborn at NantOmics
- Yulia Newton at NantOmics
- AJ Sedgewick at NantOmics
- Bobby Reddy at NantHealth
- Kayvan Niazi at NantBio
- Lennie Sender at NantKwest
