PNOC and SJCRH Collaborative DIPG Radiogenomic Investigation

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Internal funding

About this


The genetic analysis and imaging of tumors is necessary for medical professionals to diagnose and treat patients with pediatric brain cancer. Most cancer patients are imaged with CT, PET or MRI because such imaging reveals that tumors are complex, often containing many distinct subregions within them. This information allows for the classification of tumors, which guides the treatment decisions of medical professionals. Researchers hope that exploring the connections between tumor imaging and genomics will facilitate improved classification of patient tumors and better outcomes. The second goal is to develop a deeper understanding of the connection between the changes and growth of tumor subregions and changes in bodily fluids collected from the same tumors, making diagnosis, prognosis, and treatment methods more accurate and effective. The Children’s Brain Tumor Network will provide researchers with the clinical, genomic, and imaging data necessary to complete this analysis across pediatric brain cancer types.

Ask The


Ask the scientists

What are the goals of this project?

Researchers will explore the connections between tumor imaging data and genomic data and work to develop a better understanding of tumor subregions and the ways they change throughout treatment.

What is the impact of this project?

Studying these correlations between different types of pediatric brain cancer data could make diagnosis and prognosis more accurate while also opening the door to new therapeutic options.

Why is the CBTN request important to this project?

The Children’s Brain Tumor Network will be supporting researchers on this project by providing the clinical, genomic, and imaging data necessary for analysis across a broad set of pediatric brain cancer types.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing clinical, genomic and imaging data.

Explore the data in these informatics portals