Sex-specific gene expression signatures in pediatric brain tumors

Email Principal Investigator

About this


Normal human development, disease risk, and response to treatments are often different in males and females. Cancer is no exception, and we are working to determine whether cancer treatments should be optimized independently for males and females. The analysis of the CBTN's Pediatric Brain Tumor Atlas data will be a critical component of moving this important line of investigation forward.

Ask The


Ask the scientists

What are the goals of this project?

The goals of this project are to study the different mechanisms involved in male and female in pediatric neuroblastoma development and further our knowledge of the genetic components involved in the development of cancers in both children and adults.

What is the impact of this project?

Expanding this analysis to pediatrics data is needed not only to validate the previous findings, but also to better understanding the difference between children and adults.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas

Explore the data in these informatics portals