Federica Piccioni
PhD
Cambridge, MA 02142, USA
Broad Institute of MIT and Harvard
About
Group Leader
Broad Institute to MIT and Harvard
![broad 2.jpg](https://cbtn-s3.imgix.net/broad_2.jpg?auto=format&ixlib=react-9.0.3&h=80)
Broad Institute of MIT and Harvard
Cambridge, MA, USA
research
Interests
![High-grade glioma_astrocytoma (WHO grade III_IV).png](https://cbtn-s3.imgix.net/High-grade_glioma_astrocytoma_WHO_grade_III_IV.png?auto=format&ixlib=react-9.0.3&h=200)
High-Grade Glioma
High-grade Gliomas (HGG) or astrocytomas in children nearly always result in a dismal prognosis. Although novel therapeutic approaches are currently in development, preclinical testing has been limited, due to a lack of pediatric-specific HGG preclinical models. These models are needed to help test
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![Brainstem Glioma.png](https://cbtn-s3.imgix.net/Brainstem_Glioma.png?auto=format&ixlib=react-9.0.3&h=200)
Diffuse Intrinsic Pontine Glioma
A presumptive diagnosis of DIPG based on classic imaging features, in the absence of a histologic diagnosis, has been routinely employed. Increasingly however, histologic confirmation is obtained for both entry into research studies and molecular characterization of the tumor.[5] New approaches with
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