Mariarita Santi-Vicini
About
Attending Physician, Division of Neuropathology; Associate Professor of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania
Children's Hospital of Philadelphia
Pediatric brain tumors, developmental neuropathology, neurometabolic conditions and neuromuscular disease
Children’s Hospital of Philadelphia
scientific
Projects
Specimen
Ongoing
Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma
Ependymomas constitute nearly one third of the central nervous system neoplasms among children aged < 3 years1. The disease remains a significant therapeutic challenge, with a 5-year overall survival rate < 55 % among this age group2 and no available chemotherapy of proven efficacy. The breadth of t
Ependymoma
Pablo G. Cámara
Data
Molecular Analysis of the Cellular Ecosystem of Childhood Ependymoma
Ependymomas are a common form of growth in pediatric brain cancer patients, but there is a lack of effective treatment options currently available. Using the Pediatric Brain Tumor Atlas researchers will gain a greater understanding of ependymoma growth, helping to guide therapeutic opportunities.
Ependymoma
Pablo G. Cámara
Data
Ongoing
Genomic Landscape of Mixed Glial Neuronal Tumors
Mixed Neuronal-Glial Tumors (MNGT) are a benign category of tumor associated with seizures. Using the Pediatric Brain Tumor Atlas, researchers will analyze MNGT in hopes of guiding the development of treatments and predictive assessments.
DNET
Lea F. Surrey
