Genomic Landscape of Mixed Glial Neuronal Tumors
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About this
Project
Mixed Neuronal-Glial Tumors (MNGT) are a benign category of tumors found in children and young adults.They are associated with seizures and study into their genetics is an active field of research. Understanding the genetics of MNGT is vital to treatment and could help predict tumor and seizure recurrence in patients who have undergone surgery. Using the Pediatric Brain Tumor Atlas, researchers will analyze currently available genetic data on MNGT in hopes of guiding the development of treatments and predictive assessments.
Ask The
Scientists
What are the goals of this project?
Researchers seek to gain a greater understanding of the genetics of mixed neuronal-glial tumors (MNGT) to guide development of new therapies.
What is the impact of this project?
MNGT are associated with seizures in children and young adults. Understanding the genetics of these tumors could help medical professionals predict tumor growth and seizure activity, guiding the development of treatments.
Why is the CBTN request important to this project?
The Pediatric Brain Tumor Atlas contains important genomic data on many cases of MNGT that will be important for incorporation into this research.
Specimen Data
The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.
Explore the data in these informatics portals
Meet The
Team
Philadelphia, PA, USA
Florence, Italy
Philadelphia, PA, USA
Philadelphia, PA, USA
Institutions
Primary
Operations Center
Children’s Hospital of Philadelphia
Joined onOperations Center for the Children’s Brain Tumor Tissue Consortium, the Children’s Hospital of Philadelphia (CHOP) is currently ranked 1st nationally for their Pediatric Cancer Program by U.S. News & World Report. CHOP’s Biobank is home to the CBTTC’s pediatric brain and CNS tumor biorepository; the
Satellite
Meyer Children's Hospital
Joined onMeyer Children's Hospital is part of the Italian national health system, within the division of the region of Tuscany. It is integrated with the University of Florence with which it carries out care, training and research activities. Meyer has 250 beds and all pediatric medical and surgical areas.
