Associate Professor of Neurology & Neurological Sciences
Lucile Packard Children's Hospital Stanford
Michelle Monje, MD, PhD joined the faculty at Stanford University in 2011 as an Assistant Professor of Neurology & Neurological Sciences. Following her undergraduate degree in biology at Vassar College, Dr. Monje received her MD and PhD in Neuroscience from Stanford University. She then completed neurology residency at the Massachusetts General Hospital/Brigham and Women's Hospital/Harvard Medical School program. She subsequently returned to Stanford for a clinical fellowship in pediatric neuro-oncology and a postdoctoral fellowship. The scope of her research program encompasses the molecular determinants of neural precursor cell fate, neuronal-glial interactions, and the role of neural precursor cells in oncogenesis and repair mechanisms. As a practicing neurologist and neuro-oncologist, Dr Monje is dedicated to understanding the neurodevelopmental origins of pediatric brain tumors and the neurological consequences of cancer treatment.
Project Hope: High-Grade Glioma-Omics in Pediatric and AYA
Our overall objective of the project is the implementation of single-cell sequencing techniques in the context of a multiomics approach that includes bulk WGS, RNAseq, and total/phospho proteomics to investigate pediatric and AYA HGG biology. Analyses will focus on biospecimens collected across m
Brainstem glioma- Diffuse intrinsic pontine glioma
A presumptive diagnosis of DIPG based on classic imaging features, in the absence of a histologic diagnosis, has been routinely employed. Increasingly however, histologic confirmation is obtained for both entry into research studies and molecular characterization of the tumor.[