Assistant Professor of Developmental Biology in Neurological Surgery
Weill Cornell Medicine Pediatric Brain & Spine Center
Dr. Dahmane’s current research focuses a group of proteins called transcription factors that regulate how different genes are expressed during both brain development and brain cancer progression. Her laboratory has identified a critical novel transcription factor protein (called RP58) that is indispensable for brain development; its deletion in a mouse model leads to microcephaly, a birth defect affecting the size of the brain. New work from her group investigates how this protein may also be involved in brain tumor development.
Deciphering the Molecular Characteristics of Pediatric Meningiomas
Meningiomas, neoplasms of mesodermal-arachnoid origin, are the most common primary intracranial and spinal tumors. About 80% of them show benign features and are amenable to surgical resection alone. 20%, however, require extensive multimodal treatment (repeat surgery, radiotherapy, or systemic c