CBTN

Oren J. Becher

MD
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Scientific Committee
Executive Board
Principal Investigator

Chicago, IL USA

Ann & Robert H. Lurie Children’s Hospital of Chicago

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About

Attending Physician, Hematology, Oncology, Neuro-Oncology & Stem Cell Transplant

Ann & Robert H. Lurie Children’s Hospital of Chicago

My laboratory uses genetic mouse modeling tools to study Diffuse Intrinsic Pontine Glioma (DIPG), an incurable brain cancer that arises in children. Our three aims are to develop improved DIPG mouse models, to study the mechanism of novel oncogenes implicated in DIPG pathogenesis (e.g., H3K27M, ACVR1/ALK2), and to evaluate novel therapeutics

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Ann & Robert H. Lurie Children’s Hospital of Chicago

Chicago, Illinois, USA

scientific

Projects

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Data

Ongoing

Genomic Correlates with Radiation Injury…

Radiation injury can occur in pediatric brain cancer patients undergoing radiation therapy. Using data from the Pediatric Brain Tumor Atlas, researchers hope to identify genetic features that may contribute to risks for receiving radiation therapy.

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All Brain Tumor Types

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Oren J. Becher

Ann & Robert H. Lurie Children’s Hospital of Chicago
Chicago, Illinois, USA

research

Interests

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Diffuse Intrinsic Pontine Glioma…

A presumptive diagnosis of DIPG based on classic imaging features, in the absence of a histologic diagnosis, has been routinely employed. Increasingly however, histologic confirmation is obtained for both entry into research studies and molecular characterization of the tumor.[5] New approaches with

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