Visiting Graduate Assistant in Neurological Surgery
Weill Cornell Medical College
Weill Cornell Medicine
Characterizing the Blood-Brain-Barrier in Pediatric Brain Tumors
The blood brain barrier is an issue clinicians face when trying to deliver drugs for the treatment of brain cancers. Using rare samples and imaging data provided by the Children’s Brain Tumor Atlas, researchers will investigate new avenues for drug delivery.
Mark M. Souweidane
RP58 and SMARCB1 in AT/RT Pathogenesis
Atypical teratoid rhabdoid tumor (ATRT) is a common and aggressive pediatric tumor. Utilizing rare cell lines provided by the Pediatric Brain Tumor Atlas, researchers are exploring genetic alterations that could lead to more effective therapeutic strategies.
High-grade Gliomas (HGG) or astrocytomas in children nearly always result in a dismal prognosis. Although novel therapeutic approaches are currently in development, preclinical testing has been limited, due to a lack of pediatric-specific HGG preclinical models. These models are needed to help test
Low-Grade Gliomas also called astrocytomas are the most common cancer of the central nervous system in children. They represent a heterogeneous group of tumors that can be discovered anywhere within the brain or spinal cord. Although surgical resection may be curative, up to 20% of children still su