Telomere maintenance across multiple brain tumors

Email Principal Investigator
Ongoing
Data
HGG

About this

Project

We will apply different algorithms to measure research use statement telomere DNA abundance from sequencing data across tumors.We will study the association between tumor mutational background and telomere abundance

Ask The

Scientists

Ask the scientists

What are the goals of this project?

The aim of this project is to gain a better understanding of tumor heterogeneity in order to contribute to the design of future personalized medicine strategies. Specifically, I work on the integration of multiple types of genomic data derived from neuroblastoma patients to identify novel molecular groups and subsequently describe their specific genetic/epigenetic alterations and associated phenotypic effects.

What is the impact of this project?

Application of this knowledge can identify tumor vulnerabilities and opportunities for therapeutic intervention.

Specimen Data

The Children's Brain Tumor Network contributed to this project by providing access to the Pediatric Brain Tumor Atlas.

Explore the data in these informatics portals

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