Kathleen M. Schieffer
Columbus, OH USA
Nationwide Children's Hospital
About
Fellow
Nationwide Children's Hospital
Translational and computational genomics
Nationwide Children's Hospital
scientific
Projects
Data
Ongoing
Comprehensive Genomic and Immune Signature Profiling of Ependymoma and Diffuse Intrinsic Pontine Glioma
Certain subtypes of ependymoma are associated with poor outcomes as with diffuse intrinsic pontine glioma (DIPG) brain tumors. Comprehensive research into their genetics using the Pediatric Brain Tumor Atlas is being carried out by researchers in an effort to develop treatments with better outcomes.
Ependymoma, DIPG
Kathleen M. Schieffer
Data
Ongoing
Comprehensive Molecular Profiling of Pediatric Meningioma
Pediatric meningiomas are extremely rare tumors and although the mechanisms involved in one form, NF2, are well described, research into even rarer mutations is greatly needed. Specimens from the Pediatric Brain Tumor Atlas will allow researchers to study this rare tumor in an effort to develop targeted therapies for patients with YAP1 fusion meningiomas.
Meningioma
Kathleen M. Schieffer
Data
Ongoing
Comprehensive Molecular Profiling of Pediatric Diffuse Astrocytomas: Independent Validation of Proteomic Analysis
Pediatric diffuse astrocytomas are particularly hard to remove in surgery and more treatment options for patients with this type of tumor are greatly needed. Researchers will use the Pediatric Brain Tumor Atlas to conduct comparisons of tumors across age groups to further define the characteristics of this tumor type and develop more targeted therapies for pediatric brain cancer patients.
Kathleen M. Schieffer
