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About

Chief of Pediatric Neurosurgery

UPMC Children's Hospital of Pittsburgh

Ian Pollack, MD, is chief of pediatric neurosurgery at UPMC Children’s Hospital of Pittsburgh, A. Leland Albright Professor of Neurosurgery at the University of Pittsburgh School of Medicine, and co-director of the Neurosurgical Oncology Program at the Hillman Cancer Institute.

Prior to joining the faculty of the Department of Neurological Surgery at the University of Pittsburgh in 1992, he was awarded the 1991 Van Wagenen Traveling Fellowship, which afforded him a year of subspecialty training in the Department of Neurosurgery at the Hospital for Sick Children in Toronto, the Neuro-Oncology Laboratory of the University of Lausanne in Switzerland, and the Laboratory of Tumor Biology of the University of Uppsala in Sweden.

Dr. Pollack graduated magna cum laude from Emory University in 1980, where he earned a BS degree in chemistry. He received his medical degree from the Johns Hopkins University School of Medicine in 1984, then completed a surgical internship and neurosurgical residency at the University of Pittsburgh School of Medicine. He also was a research fellow in neuropathology and neurobiology during some of that time.

Dr. Pollack has published more than 350 papers in refereed journals, numerous book chapters and invited papers, and has edited two books on childhood brain tumors. He is co-editor of the book Principles and Practice of Pediatric Neurosurgery—currently in its third edition—and an accompanying atlas Operative Techniques In Pediatric Neurosurgery.

He is currently a principal investigator on NIH grants focusing on novel therapies for brain tumors and evaluating molecular markers of tumor prognosis.

Dr. Pollack was named vice chairman of academic affairs for the department in July of 2008 and Distinguished Professor of Neurosurgery at the University of Pittsburgh in 2015. He also chaired the Children’s Oncology Group CNS Tumor Committee from 1999-2009, and co-chaired the National Cancer Institute Brain Malignancy Steering Committee between 2010 and 2017.

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UPMC Children's Hospital of Pittsburgh

Pittsburgh, PA, USA

scientific

Projects

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Specimen

Ongoing

Elucidating the Somatic Epigenetic Landscape of Pediatric Meningioma and Schwannoma

Pediatric tumors have unique properties compared to adult tumors, requiring different treatment strategies for the same tumor type. Using samples provided by the Children’s Brain Tumor Network, researchers will carry out comprehensive comparisons of pediatric meningioma and schwannoma to map these critical areas to develop novel treatments.

Meningioma, Schwannoma

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Sameer Agnihotri

UPMC Children's Hospital of Pittsburgh
Pittsburgh, PA, USA
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Data

Ongoing

Landscape of Tumor-infiltrating T cell Repertoire of Pediatric Brain Tumors

Understanding the incidence and classification of T cell receptors of pediatric brain tumors is necessary to develop new therapies. Using data from the Pediatric Brain Tumor Atlas, researchers seek to better understand the tumor cellular immune system.

All Brain Tumor Types

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Gary Kohanbash

UPMC Children's Hospital of Pittsburgh
Pittsburgh, PA, USA
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Specimen

Ongoing

Integrated Genomic Analysis to Elucidate the Role of PIKC3A and 10q LOH as Unique Drivers and Cooperating Events in Pediatric High-grade Gliomas

We have previously reported a high frequency of AKT activation, a downstream target of PTEN, in pediatric high-grade gliomas (pHGGs), as assessed by immunohistochemistry (IHC), and demonstrated that this was associated with an adverse prognosis. Compared to adult high-grade gliomas, pHGGs show a low

HGG

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Ian Pollack

UPMC Children's Hospital of Pittsburgh
Pittsburgh, PA, USA