Accelerating childhood brain tumor research to faster cures
Over 30 types of pediatric brain and spinal cord tumor clinical and molecular data, biospecimens, and cell-lines are available at no cost to academic researchers. Our open science model has shortened research time by up
to 20 years.
By working together to collect and share resources, we can save more children.
CBTN by the Numbers
Brain and CNS tumors are the most common cause of disease related death in children aged 0–19 years in the U.S. and across the globe, with approximately 412,000 children and young adults living with a brain tumor each year.
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Scientific Projects
Specimen
Ongoing
Gene Expression Analysis Platform
Evaluation for FFPE Specimen M…
Newly developed technology is advancing the
ability of researchers to gain important insight
from small clinical specimens.
ability of researchers to gain important insight
from small clinical specimens.
Medulloblastoma, HGG
Mateusz Koptyra
Children’s Hospital of Philadelphia
Philadelphia, PA, USA
Data
Specimen
Ongoing
Proteogenomic Identification of
Structural Variations
Changes to DNA that can give rise to cancers
often create fusion proteins, proteins that may
be useful as therapeutic targets. Using data from
the Pediatric Brain Tumor Atlas, researchers wil…
often create fusion proteins, proteins that may
be useful as therapeutic targets. Using data from
the Pediatric Brain Tumor Atlas, researchers wil…
Medulloblastoma, DIPG
Brian Rood
Children’s National Hospital
Washington, DC, USA
Data
Ongoing
Deciphering the Molecular
Characteristics of Pediatric Meni…
Pediatric meningiomas are extremely rare
tumors and are often of an aggressive form
unresponsive to available treatments.
Specimens from the Pediatric Brain Tumor Atla…
tumors and are often of an aggressive form
unresponsive to available treatments.
Specimens from the Pediatric Brain Tumor Atla…
Medulloblastoma, HGG, LGG, Ependymoma,
Meningioma, Schwannoma
Meningioma, Schwannoma
Nadia Dahmane
Weill Cornell Medicine
New York, NY, USA
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Data Science
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Available Resources
Craniopharyngioma
Childhood craniopharyngiomas are rare tumors
usually found near the pituitary gland (a
pea-sized organ at the bottom of the brain that
controls other glands) and the hypothalamus (…
usually found near the pituitary gland (a
pea-sized organ at the bottom of the brain that
controls other glands) and the hypothalamus (…
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Medulloblastoma
Medulloblastomas comprises the vast majority of
pediatric embryonal tumors and by definition
arise in the posterior fossa, where they constitute
approximately 40% of all posterior fossa tumor…
pediatric embryonal tumors and by definition
arise in the posterior fossa, where they constitute
approximately 40% of all posterior fossa tumor…
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High-Grade Glioma
High-grade Gliomas (HGG) or astrocytomas in
children nearly always result in a dismal
prognosis. Although novel therapeutic
approaches are currently in development, prec…
children nearly always result in a dismal
prognosis. Although novel therapeutic
approaches are currently in development, prec…
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