Chief of Pediatric Neurological Surgery
UCSF Benioff Children's Hospital
Dr. Nalin Gupta, chief of pediatric neurological surgery at UCSF Benioff Children's Hospital, is an expert in the evaluation and surgical management of neurological disorders in children, including epilepsy, brain tumors, hydrocephalus, and cranial and spinal birth defects.
Nalin's primary research focuses on the role of inflammation in brain tumor progression. He is a principal investigator of the Brain Tumor Research Center at UCSF. He also is involved in national clinical studies of brain tumors and the effectiveness of fetal surgery for spina bifida.
Nalin earned his medical degree and completed residency training in neurological surgery at the University of Toronto. He completed fellowship training in pediatric neurosurgery at the Hospital for Sick Children. He also has a doctorate in biophysics from UCSF. He served as an attending neurosurgeon at the University of Chicago before coming to UCSF.
High-grade glioma/astrocytoma (WHO grade III/IV)
High-grade Gliomas (HGG) in children nearly always result in a dismal prognosis. Although novel therapeutic approaches are currently in development, preclinical testing has been limited, due to a lack of pediatric specific HGG preclinical models. These models are needed to help test the effective
Brainstem glioma- Diffuse intrinsic pontine glioma
A presumptive diagnosis of DIPG based on classic imaging features, in the absence of a histologic diagnosis, has been routinely employed. Increasingly however, histologic confirmation is obtained for both entry into research studies and molecular characterization of the tumor.[