Mariella Filbin
About
Research Co-Director, Pediatric Neuro-Oncology Program; Assistant Professor of Pediatrics, Harvard Medical School; Physician
Dana-Farber Cancer Institute
Dr. Mariella Filbin is the Research Co-Director at Harvard Medical School. She received her MD and PhD in biochemistry and molecular biology from the Medical University of Graz, Austria. Following graduation she completed her pediatric residency at the Boston Children's Hospital and completed a fellowship in pediatric hematology/oncology at Dana-Farber/Boston Children's Cancer and Blood Disorders Center. She joined the faculty at Dana Farber/Boston Children's as
a pediatric neuro-oncologist in July 2017.
Dr. Filbin's research is focused establishing cellular networks of tumor dependencies in pediatric brain tumors with the goal of finding new targeted therapies.
scientific
Projects
research
Interests
HGG
High-Grade Glioma
High-grade Gliomas (HGG) or astrocytomas in children nearly always result in a dismal prognosis. Although novel therapeutic approaches are currently in development, preclinical testing has been limited, due to a lack of pediatric-specific HGG preclinical models. These models are needed to help test
Ependymoma
Ependymoma
Ependymomas arise from ependymal cells that line the ventricles and passageways in the brain and the center of the spinal cord. Ependymal cells produce cerebrospinal fluid (CSF). These tumors are classified as supratentorial or infratentorial. In children, most ependymomas are infratentorial tumors
